Key HIV drug 'failing in Africa'

LONDON - Strains of HIV are becoming resistant to an antiretroviral drug commonly used to prevent and fight the virus, research has suggested.

HIV was resistant to the drug Tenofovir in 60% of cases in several African countries, according to the study, covering the period from 1998 to 2015.

The research, led by University College London, looked at around 2,000 HIV patients worldwide.

Lead author Dr Ravi Gupta said the results were "extremely concerning".

'Right levels'

The work, which took four years to complete, was started in 2012 and compared patients with HIV in Africa with those in Europe.

Splitting the sample size roughly into two groups the study found that in Africa 60% of patients were resistant to Tenofovir, whereas in Europe the figure was only 20%.

The paper, which has been published in The Lancet Infectious Diseases journal, said poor administration of the drug, in terms of regularly taking the right levels of Tenofovir could be explanation for the discrepancy.

"If the right levels of the drug are not taken, as in they are too low or not regularly maintained, the virus can overcome the drug and become resistant," Dr Gupta told the BBC News website.

"Tenofovir is a critical part of our armamentarium against HIV, so it is extremely concerning to see such a high level of resistance to this drug," he added.

The paper also suggested that Tenofovir-resistant strains of HIV could be passed on from person to person.

"We certainly cannot dismiss the possibility that resistant strains can spread between people and should not be complacent. We are now conducting further studies to get a more detailed picture of how Tenofovir-resistant viruses develop and spread," Dr Gupta said.

HIV is the world's most deadly infectious disease, according to the World Health Organization (WHO).

Dr Gupta said a global effort and an cash investment would be needed to provide better facilities and monitoring in poorer African countries and that it was in everyone's interests to make this happen.

Comments (8)

@samson I wonder if by any chance you are to discover some alluvial diamonds in your back-yard or garden , if you will come on this plattform to drop your address and invite the world to come to scrap for the precisoius stones and make a testimony. HIV is dangerous and its up to the people involved in sexual activity to insist on protection and safe sex.

X-MAN IV - 29 January 2016

how true is it that u were HIV positive and by use of herbs now you are negative please shade more light and your details before many people lose their money for this is a serious matter which the world is affected with

affirn sindano - 1 February 2016

sometimes it is good to find a ground to play on than mislead those who are not sure,come into the open and gvt gives your herb Dr authority to run clinical trials with clients consent.

ngwex - 8 February 2016

Please do not be cheated. These are Nigerians. Code 234 is for Nigeria

Tendai Nyarai - 10 February 2016

I never believed i would be healed someday.This disease started circulate all over my body and i have been taking treatment from my doctor, few weeks ago i came on search on the internet if i could get any information concerning the prevention of this disease, on my search i saw a testimony of someone who has been healed from (Hepatitis B and Cancer) by this Man dr.okorom and she also gave the email address of this man and advise we should contact him for any sickness that he would be of help, so i wrote to telling him about my (HERPES Virus) he told me not to worry that i was going to be cured!! hmm i never believed it,, well after all the procedures and remedy given to me by this man few weeks later i started experiencing changes all over me as the Dictor Shapson assured me that i have cured,after some time i went to my Dr to confirmed if i have be finally healed behold it was TRUE, So friends my advise is if you have such sickness or any other at all you can email dr.okorom on : or

Sharon Matas - 11 February 2016

What a great man, a great thanks to DR.OMOA the man that bring me out of this sorrow this is the man that can as well help the world, on this diseases I can remember 5 year ago when I was searching for cure, and how I have spent much money and I finally lost hope due to my conduction I have to put my hope on god, lucky to me last week here I was on the internet, check on how many year I can spent on earth them I see a comment about this great man DR.OMOA what a lucky day for me and today am giving my testimony about him I have never believe there is cure at all, but this man just want me to give him a try, if he cannot do it I will know his is not DR.OMOA that he have been doing this cure for more than many year now I put my hope on him and also my dear god but today am very happy to give this story to you all, it all happen when I was 23 year well because of this disease I can get married and very happy today am now negative I can get married now to my follow people that is on my shoes this the good way to say bye to this diseases HIV/AIDS contact this man now ( ( +2348141309378

helen - 15 February 2016

Hello my dear viewers,I am Erick Stuardo, i will say to the world to celebrate with me on this numerous testimony, i never believe i could ever get rid of this horrible disease until one fateful day,my story and appreciation goes to Dr.Oduma the powerful great doctor that help me to cure my HIV/AIDS disease from my life,he is truly a truthful man with high herbs power's he uses on saving people's life, just a few days back i came in contact with Dr.Oduma emails which many individuals have testify so much about of his kind work, so i decided and contacted him quickly because the disease was almost at the last minute of taking my life, i have tried all remedies from several physicians from hospitals but none could help me apart from Dr.Oduma who finally cure my HIV/AIDS disease, i was amazed and overwhelmed when the doctor confirmed me negative in the same hospital i have been before,i wish to anyone that is sick today and want healing to please contact this doctor ( so if you have any problem HIV, HERPES, CANCER, ALS,HEPATITIS B, DIABETIC,or call +2348071622572.

Erick Stuardo - 16 March 2016

contact.dr,for all kinds of disease ..

pearl - 7 July 2016

Post a comment

Readers are kindly requested to refrain from using abusive, vulgar, racist, tribalistic, sexist, discriminatory and hurtful language when posting their comments on the Daily News website.
Those who transgress this civilised etiquette will be barred from contributing to our online discussions.
- Editor

Your email address will not be shared.
Enter the three characters from the image on the right. This helps prevent automated 'bots' from submitting spam to the site. This field is NOT case-sensitive. If the characters are a bit hard to see, try refreshing the code by clicking the image.